healthy4u

Help and learn from others as you browse the web: Google Sidewiki

As you browse the web, it's easy to forget how many people visit the same pages and look for the same information. Whether you're researching <a href="http://www.google.com/sidewiki/entry/117213073072448275065/id/Fegil0nf8ivzC6iIB8MU0XREs3A">advice on heart disease prevention</a> or looking for <a href="http://www.google.com/sidewiki/entry/oklahomazeppelin/id/Dys9NgtwlW1uI1a1-R8-grlgxOw">museums to visit in New York City</a>, many others have done the same and could have added their knowledge along the way. What if everyone, from a local expert to a renowned doctor, had an easy way of sharing their insights with you about any page on the web? What if you could add your own insights for others who are passing through? Now you can. Today, we're launching Google Sidewiki, which allows you to contribute helpful information next to any webpage. Google Sidewiki appears as a browser sidebar, where you can read and write entries along the side of the page. <object height="340" width="560"><param name="movie" value="http://www.youtube.com/v/CsjJOsx84MA&hl=en&fs=1&"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><embed src="http://www.youtube.com/v/CsjJOsx84MA&hl=en&fs=1&" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="560" height="340"></embed></object> In developing Sidewiki, we wanted to make sure that you'll see the most relevant entries first. We worked hard from the beginning to figure out which ones should appear on top and how to best order them. So instead of displaying the most recent entries first, we rank Sidewiki entries using an algorithm that promotes the most useful, high-quality entries. It takes into account feedback from you and other users, previous entries made by the same author and many other signals we developed. If you're curious, you can <a href="http://googleresearch.blogspot.com/2009/06/large-scale-graph-computing-at-google.html">read more</a> on our Google Research Blog about the infrastructure we use for ranking all entries in real-time. Under the hood, we have even more technology that will take your entry about the current page and show it next to webpages that contain the same snippet of text. For example, an entry on a speech by President Obama will appear on all webpages that include the same quote. We also bring in relevant posts from blogs and other sources that talk about the current page so that you can discover their insights more easily, right next to the page they refer to. We're releasing Google Sidewiki as a feature of Google Toolbar (for Firefox and Internet Explorer) and we're working on making it available in Google Chrome and elsewhere too. We also have the first version of our <a href="http://code.google.com/apis/sidewiki/">API</a> available today to let anyone work freely with the content that's created in Sidewiki. We've been testing Sidewiki with several experts and news organizations for a while and are happy to <a href="http://www.google.com/sidewiki/intl/en/testimonials.html">hear their positive responses</a>. We hope you'll try it for yourself, <a href="http://twitter.com/googlesidewiki">follow our Twitter feed</a>, and let us know what you think! If you're ready to start exploring the web with Google Sidewiki, visit <a href="http://google.com/sidewiki/#tbbrand=GZEG">google.com/sidewiki</a> to download Google Toolbar with Sidewiki and contribute your own entries alongside pages on the web. Posted by Sundar Pichai, VP Product Management and Michal Cierniak, Engineering Lead for Google Sidewiki

Help and learn from others as you browse the web: Google Sidewiki

As you browse the web, it's easy to forget how many people visit the same pages and look for the same information. Whether you're re...

Đọc thêm »

Picasa 3.5, now with name tags and more

Today, I'm happy to announce that <a href="http://googlephotos.blogspot.com/2009/09/announcing-picasa-35-now-with-name-tags.html">we're releasing</a> Picasa 3.5, a new version of our free photo editing software. This version gives you the ability to add name tags to your photos, using the same facial recognition technology that powers <a href="http://picasa.google.com/features-nametags.html">name tags on Picasa Web Albums</a>. Name tags are designed to help you organize your photos by what matters most: the people in them. Picasa identifies similar faces and puts these into an "Unnamed People" album. From there, you can easily add a name tag by clicking "Add a name" and typing the person's name. After you've added name tags to some photos, you can use your tags to do creative things, like quickly find all the photos with the same two people in them, make a face collage with just one click or upload and share people albums with friends. In addition to name tags, Picasa 3.5 has integrated Google Maps, so you can easily geotag your photos or view the locations of already-tagged photos on a map. And using our totally redesigned import process, you can now import photos from your camera and upload the photos to Picasa Web Albums in one easy step. <object height="340" width="560"><param name="movie" value="http://www.youtube.com/v/gYO2uhrIZJ4&hl=en&fs=1&"><param name="allowFullScreen" value="true"><param name="allowscriptaccess" value="always"><embed src="http://www.youtube.com/v/gYO2uhrIZJ4&hl=en&fs=1&" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="560" height="340"></embed></object> Picasa 3.5 is available for both PC and Mac, in English for now. You can download and try it today at <a href="http://picasa.google.com/">picasa.google.com</a>. Posted by Todd Bogdan, Software Engineer

Picasa 3.5, now with name tags and more

Today, I'm happy to announce that we're releasing Picasa 3.5, a new version of our free photo editing software. This version gives ...

Đọc thêm »

Google climate change tools for COP15

In December of this year, representatives from nations around the globe will gather in Copenhagen to discuss a global agreement on climate change. The objective is to reduce global warming emissions sufficiently in order to avoid the most severe impacts of climate change and to support the global community in adapting to the unavoidable changes ahead. Denmark will act as host for this fifteenth Conference of the Parties under the United Nations’ Climate Change Convention, known as <a href="http://www.cop15.dk/">COP15</a>. <a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgUxcjfkItWdSzO9e_yLZOk6dHeL4KXeVYb8Sc7N5DhxawQzzFeMzu7pj4ePfh4_QAp21uv8ykfTUkNofdKy2WIiAUTigpyBICynuDkpPGWb4IiKepmWHO3CmdUKA-oaqEsw7ENXy7Gs2uB/s1600-h/cop15geo_blog_post1.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5384306859347464418" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgUxcjfkItWdSzO9e_yLZOk6dHeL4KXeVYb8Sc7N5DhxawQzzFeMzu7pj4ePfh4_QAp21uv8ykfTUkNofdKy2WIiAUTigpyBICynuDkpPGWb4IiKepmWHO3CmdUKA-oaqEsw7ENXy7Gs2uB/s320/cop15geo_blog_post1.jpg" style="margin: 0pt 0pt 10px 10px; float: right; cursor: pointer; width: 289px; height: 320px;" /></a>In collaboration with the Danish government and others, we are launching <a href="http://www.google.com/cop15">a series of Google Earth layers and tours</a> to allow you to explore the potential impacts of climate change on our planet and the solutions for managing it. Working with data from the Intergovernmental Panel on Climate Change (<a href="http://www.ipcc.ch/">IPCC</a>), we show on Google Earth the range of expected temperature and precipitation changes under different global emissions scenarios that could occur throughout the century. Today we are unveiling our first climate tour on Google Earth: "<a href="http://www.youtube.com/watch?v=jPIo7lteCZk&hd=1">Confronting Climate Change</a>," with narration by Al Gore. Stay tuned for more tours in the coming weeks! Together with the Danish government, we're also launching our <a href="http://www.youtube.com/cop15">YouTube COP15 channel</a>. On the channel, you can submit your thoughts and questions on climate change to decision-makers and the world through an initiative called "Raise Your Voice." These videos will be broadcast on screens around the conference in December and rated by viewers of the channel. The top-rated contributions will be aired globally during the COP15 CNN/YouTube debate on December 15th, and the top two submissions will win a trip to Copenhagen. We look forward to seeing your videos! Posted by Benjamin Kott, Green Business Operations and Jonas Vang, Industry Analyst

Google climate change tools for COP15

In December of this year, representatives from nations around the globe will gather in Copenhagen to discuss a global agreement on climate c...

Đọc thêm »

A "Safety-Net" Medical Center CEO Gets a Golden Parachute

<a href="http://www.thebostonchannel.com/investigative/20987735/detail.html">From theBostonChannel.com </a>comes this story on executive compensation in a not-for-profit health care organization, <blockquote> Boston Medical Center – a financially troubled hospital – gave its outgoing CEO a one-time, nearly $3.5 million payment, in addition to her $1.3 million annual salary, Team 5 Investigates reported Friday. Elaine Ullian, 61, has led the city’s major 'safety net' hospital for the last 15 years. She recently announced she will retire when her contract expires in January. The hospital's financial situation is such that hospital leaders say it could face closure in the years ahead. It is currently suing the Executive Office of Health and Human Services over how it gets paid for treating poor and uninsured patients. Team 5 Investigates discovered, in a review of the hospital’s financial filings with the state, that Ullian was paid $3,466,458 'in recognition of exceptional performance over a period of 15 years.' The nearly $3.5 million bonus was on top of Ullian’s 2008 compensation of $1,348,504 including salary and benefits. In a written statement to Team 5 Investigates, Ted English, the chairman of BMC’s board said that Ullian’s 'compensation is set by a committee of the Boston Medical Center Board of Trustees who consult with independent compensation advisors. It is based on her performance evaluation and measurable goals that are reviewed annually.' 'The Board considers Elaine Ullian to be one of the most competent and successful hospital CEOs in the country and believes she is primarily responsible for the success of Boston Medical Center over the past 15 years,' English's statement said. </blockquote> Boston Medical Center was formed by the merger of University Hospital (the Boston University teaching hospital), and Boston City Hospital, the legendary municipal hospital. (Note: I served as an internal medicine intern and resident in the University Hospital program, and rotated through Boston City frequently.) Thus, as noted above, BMC is the city's primary "safety net" hospital for the care of the poor. BMC has for <a href="http://www.bmc.org/about/who/mission.htm">its mission</a>: <blockquote> We will provide consistently excellent and accessible health services to all in need of care regardless of status or ability to pay – exceptional care, without exception. </blockquote> Such generous pay seems inconsistent with this mission and the organization's not-for-profit status. Such a golden parachute seems inconsistent with the current threats to its finances. Any worry about the CEO's retirement finances should further be reduced by her ongoing part-time work on the boards of directors of three public for-profit health care corporations, <a href="http://www.hologic.com/">Hologic</a>, a medical device company specializing in "womens' health," <a href="http://www.thermofisher.com/global/en/home.asp">ThermoFisher Scientific</a>, a manufacturer of laboratory equipment and supplies for health care and research, and <a href="http://www.vrtx.com/">Vertex Pharmaceuticals</a>, a biotechnology company focusing on small-molecule drugs. For her work as a director of Hologic, she received $304,698 in total compensation in 2008, and owned 40,000 shares or equivalent of common stock (per the company's <a href="http://www.sec.gov/Archives/edgar/data/859737/000119312509009496/ddef14a.htm">2009 proxy statement</a>). For her work for ThermoFisher Scientific, she received $275,319 total compensation, and owned 61,068 shares or equivalent (per the <a href="http://ccbn.10kwizard.com/xml/download.php?repo=tenk&ipage=6256980&format=PDF">2009 proxy statement</a>). For her work for Vertex Pharmaceuticals, she received $337,480 total compensation, and owned 79,500 shares or equivalent (per the <a href="http://investors.vrtx.com/secfiling.cfm?filingID=1047469-09-3942">2009 proxy statement</a>). As Robert AG Monks put it, corporate directors are supposed to "demonstrate unyielding loyalty to the company's shareholders" [Per Monks RAG, Minow N. <a href="http://www.amazon.com/Corporate-Governance-Robert-G-Monks/dp/1405116986">Corporate Governance</a>, 3rd edition. Malden, MA: Blackwell Publishing, 2004. P.200.] Therefore, Ms Ullian's directorships seem to pose conflicts with her primary employment as CEO of an academic medical center which must buy products used in womens' health, buy laboratory supplies, and implement basic and clinical research. The BMC board chair's assertion that the CEO is "primarily responsible for the success" of the institution merits special comment. It seems obvious that the main determinant of the success of a medical center is the work done by its health care professionals and support personnel. A medical center cannot provide care, much less good care, without doctors, nurses, therapists and technicians, supported by supply, logistics, cleaning, maintenance, dietary, clerical, medical record, financial and yes, even health care information technology workers and systems (and if I left out an important group of support personnel, I apologize now.) The chair's assertion suggests the hubris central to the ethos of contemporary business managers, but is at odds with the clinical context. (Of course, if the CEO was primarily responsible for the organization's success, she should now shoulder primary blame for its current awkward financial situation, but such consistency may be the hobgoblin of minds too little to understand the gravitas of the C-level manager.) A long time ago, in a galaxy far, far away, health care was a calling. Doctors once pledged to avoid all commercialization (see post <a href="http://hcrenewal.blogspot.com/2009/06/why-did-us-physicians-give-up-their.html">here</a>), and hospital directors or superintendents (not CEOs) did not earn riches, much less become "imperial." (See Ludmerer's <a href="http://www.oup.com/us/catalog/general/subject/HistoryOther/HistoryofMedicine/?view=usa&ci=9780195181364">Time to Heal</a>.) But in the culture of wretched excess that spread from the financial world, hospital CEOs now seem to feel entitled to become wealthy, as they claim responsibility for all successes, while all failures are blamed on someone else. The current system has made hired managers into an ersatz aristocracy, entitled to fill their pockets while denying any responsibility for ever rising costs, declining access, poor quality and demoralized professionals. In my humble opinion, to achieve true health care reform, health care again must become a calling, lead by people who will put the mission ahead of the accumulation of wealth and power.

A "Safety-Net" Medical Center CEO Gets a Golden Parachute

From theBostonChannel.com comes this story on executive compensation in a not-for-profit health care organization, Boston Medical Center – a...

Đọc thêm »

Physicians, Even Those Educated in IT and Informatics, Are Not "Real" IT People

I've been participating in the comment thread on the HisTALK heath IT industry news/gossip site at <a href="https://exchangeweb.drexel.edu/owa/redir.aspx?C=6e88815ddf904c1088c4e7892352e56a&URL=http%3a%2f%2fhistalk2.com%2f2009%2f09%2f17%2fnews-91809%2f" target="_blank">http://histalk2.com/2009/09/17/news-91809/</a> . At this time there are 40 comments - mine start at #4. (I've also archived the thread in Word format <a href="http://www.ischool.drexel.edu/faculty/ssilverstein/Responses%20to%20HISTALK%20News%2009_18_09.doc">here</a>.) It's been quite interesting, demonstrating that many of the harmful attitudes of IT personnel about healthcare I observed more than a decade ago are still around. An anonymous commenter under the title "Programmer" has been forthcoming with views I think are actually common in the health IT field about medicine, science, IT flaws and shortcomings, and physician involvement in HIT. I will let you read them for yourself at the above link. Others have indicated in that comment thread and other threads that "Programmer" is an executive with a large HIT company, but I cannot confirm this. Among other stunning views, this commenter exhibited: <ul><li>Serious errors in logic such as repeatedly and unshakably mistaking well-documented reports about known rates of IT project failure as a condemnation that all IT projects fail, perhaps reflecting a state of denial; </li><li>Lack of understanding that in scientific fields such as biomedicine, conclusions generally should be supported by reasonable evidence, not "because I think so"; </li><li>Lack of understanding and dismissal of the value of the peer reviewed scientific literature on health IT, and further, a seeming inability or unwillingness to peruse the "references" section of scientific articles, a profoundly unscientific approach to the world; </li><li>Dismissal of the written views of organizations such as the Joint Commission, US National Research Council, European Federation for Medical Informatics and others on HIT deficiencies; </li><li>Perhaps most harmfully, dismissal of faulty conceptual and physical data models, inadequate workflow and cognitive support, and IT of poor user interaction design that presents a mission hostile user experience as a real problem in critical care areas such as Invasive Cardiology (specifically, in <a href="http://www.ischool.drexel.edu/faculty/ssilverstein/failurecases/?loc=cases&sloc=Cardiology%20story">this case</a>). Instead, this IT person dismissed physician dismay and rejection of such ill-designed and profoundly unusable IT as a mere "pissing contest" between IT and clinicians, consistent with narrow, territorial, paternalistic, indeed autocratic IT-centric views and a reversal of enabler (clinician) vs. facilitator (IT service provision) roles in patient care.</li></ul> "Programmer" also attacks (from the perspective of arrogant ignorance) the "<a href="http://www.jamia.org/cgi/content/full/16/3/291">Health IT Project Success and Failure: Recommendations from Literature and an AMIA Workshop</a>" white paper drawing together the thinking at a workshop attended by over fifty informatics experts from all areas of medicine and technology. The role of the medical informatics expert itself, and other issues as well relating to reasons for HIT failure and difficulty are attacked and dismissed. (If the person is a fake or "sock puppet", they're doing a mighty accurate approximation of my own uncomfortably-common observations in managing health IT and biomedical research IT projects while working with non-biomedical IT personnel, see cases <a href="http://www.ischool.drexel.edu/faculty/ssilverstein/failurecases/?loc=home">here</a>.) The crux of the matter came out towards the end where "Programmer" maintains in Comment #28 that I am "just someone who likes to talk about IT” and he is a “real IT person.” A "real IT person?" I've heard that before: this is the "doctors don't do things with computers" (including medical informaticists) type of comment I've heard face-to-face periodically from healthcare IT personnel since I entered the field in the early 1990's, and commented upon a decade ago <a href="http://www.ischool.drexel.edu/faculty/ssilverstein/informaticsmd/tactics.htm#dddtwc">here</a>. I've emailed Tim, the proprietor of the HISTalk site [mr_histalk AT yahoo.com], to inquire if this poster was real or just a provocateur. Tim's response: "He's real and has been around for awhile, although lately he seems to be enjoying an escalated level of confrontation when he can create one." I maintain -- based on personal experience and that told me by others -- that this person's views are not all that rare in the HIT vendor and hospital IS communities. I also opine that thinking such attitudes can be dealt with by logical argument and persuasion is a belief itself lacking in rigor. IT personnel of views as in the HisTALK comments thread represent an older culture of data processing, dating from the days of card punch tabulators that ran businesses prior to computers. It is a culture that has failed to mature with the times. As I wrote <a href="http://hcrenewal.blogspot.com/2008/05/seedie-society-for-exorbitantly.html">here</a>, the unimaginative, process over results, tight fisted control, bureaucratic data-processing culture of the business IT (management information systems) world is the lineal descendant of <a href="http://www.columbia.edu/acis/history/tabulator.html">IBM's patchcord plug-panel programmed, card tabulating machines</a> from which IBM made a large portion of their profit in the days before the electronic computer: <div style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgtzPSYfQOl-r_AY2tMvOiNYhzoGThK0-_X7Xy_KAOQYMox-IK8N8u3Lz-n7cwYwbkDrau7lm2ya8P8S_uYDp9EylhKIFfAq-ltb5zgOjz-LSciW7IPT-SLXr4YvJ2KYVpSqpkY1rMh3qBg/s1600-h/tabulator.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5384014906855078690" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgtzPSYfQOl-r_AY2tMvOiNYhzoGThK0-_X7Xy_KAOQYMox-IK8N8u3Lz-n7cwYwbkDrau7lm2ya8P8S_uYDp9EylhKIFfAq-ltb5zgOjz-LSciW7IPT-SLXr4YvJ2KYVpSqpkY1rMh3qBg/s320/tabulator.jpg" style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 222px; height: 145px;" /></a>Hollerith Type III Tabulator with its control panel exposed. Photo: MNRAS, Vol.92, No.7 (1932). Click to enlarge. </div> Fortunately, such personnel and their designer-centric, as opposed to user- and work-centric philosophies are starting to become obsolete. This can be observed (as an example) via the mission of the <a href="http://www.ischools.org/">iSchool consortium</a>, of which my organization, the Drexel College of Information Science and Technology, is a member: <blockquote>The iSchools are interested in the relationship between information, people and technology. This is characterized by a commitment to learning and understanding the role of information in human endeavors. The iSchools take it as given that expertise in all forms of information is required for progress in science, business, education, and culture. This expertise must include understanding of the uses and users of information, as well as information technologies and their applications. [the order of these priorities is pertinent - ed.]</blockquote> Unfortunately, the data processing culture and its adherents are not becoming obsolete quite fast enough. There are still too many in the upper echelons of management, including health IT vendors, hospitals and pharmaceutical R&D environments. Finally, IT personnel with such attitudes as displayed in the comments, from the lowliest programmer to the CEO and Board, have no place anywhere near where patient care is conducted, or where information systems serving clinical medicine are designed and built. In line with other character types one encounters in healthcare that are often discussed on Healthcare Renewal, clinicians should not accommodate such IT personnel and these types of views. -- SS Addendum: The final (at this time) comment, #40, left by the above commenter states: <blockquote> #40 Programmer: If I decide to become a medical informatproctolicist, I’m going to specialize in sardonicology.</blockquote> IT personnel of such views bring to life Lecia Barker's paper "Defensive climate in the computer science classroom": <blockquote>“Defensive climate in the computer science classroom” by Barker et al., <st1:place st="on"><st1:placetype st="on">Univ.</st1:placetype> of <st1:placename st="on">Denver</st1:placename></st1:place>. Link <a href="http://portal.acm.org/citation.cfm?id=563354&coll=portal&dl=ACM">here</a> (subscription required). May help explain the control-seeking culture of IT personnel. As part of an NSF-funded IT workforce grant, the authors conducted ethnographic research to provide deep understanding of the learning environment of computer science classrooms. Categories emerging from data analysis included 1) impersonal environment and guarded behavior; and 2) the creation and maintenance of informal hierarchy resulting in competitive behaviors. These communication patterns lead to a defensive climate, characterized by competitiveness rather cooperation, judgments about others, superiority, and neutrality rather than empathy.</blockquote> -- SS

Physicians, Even Those Educated in IT and Informatics, Are Not "Real" IT People

I've been participating in the comment thread on the HisTALK heath IT industry news/gossip site at http://histalk2.com/2009/09/17/news-9...

Đọc thêm »

Wyeth, Ghostwriting, Dr. Joseph Camardo and a Big Liquor Store With a Little Grocery Department

Ghostwriting is a topic covered extensively at Healthcare Renewal, including at my post "Wyeth: Ghostwritten Papers Fake, But Accurate" <a href="http://hcrenewal.blogspot.com/2009/07/wyeth-ghostwritten-papers-fake-but.html">here</a>, Roy Poses' "Wyeth's Industrial Scale Ghost-Writing" <a href="http://hcrenewal.blogspot.com/2009/08/wyeths-industrial-scale-ghost-writing.html">here</a>, and many others about Wyeth and other pharmas that can be viewed via this link: <a href="http://hcrenewal.blogspot.com/search/label/ghost%20writing">http://hcrenewal.blogspot.com/search/label/ghost writing</a>. A story in the Philadelphia Inquirer yesterday about Wyeth and ghostwriting brought to mind my medical school days at Boston University, in a metaphorical and rather negative way, regarding an oddity reflecting today's pharma industry. In those years I lived next to Boston City Hospital on the top floor of a 29-story high rise at 35 Northampton Street, at that time one of the toughest and highest crime neighborhoods in the region if not the country (I was careful and lucky, and only got mugged at gunpoint once.) I had an excellent bird's-eye view of the urban decay in the area, reflective of ethical decay in the community. <div style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7vNBFn1J7Bb7S6KLdAmIjH6aiXSl7CjnfwJg4EsGq-QPlmRvxKG4XTGpzN7bfX-ftFuAruX9UmdPFKv3LJ9n0X1VdjfsPhE9Z_sqtoc_35gbYgASZ6WH43vQr6VFEk-8ikjZX8ZHpQLmu/s1600-h/35_northampton.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5383914860418843218" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7vNBFn1J7Bb7S6KLdAmIjH6aiXSl7CjnfwJg4EsGq-QPlmRvxKG4XTGpzN7bfX-ftFuAruX9UmdPFKv3LJ9n0X1VdjfsPhE9Z_sqtoc_35gbYgASZ6WH43vQr6VFEk-8ikjZX8ZHpQLmu/s320/35_northampton.jpg" style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 320px; height: 182px;" /></a>35 Northampton St., next to Boston Medical Center (formerly Boston City Hospital) </div> Across the street from the high rise was an oddity - a very large liquor store named Blanchard's. Inside Blanchard's was a very small grocery department of all things. Have a snack with your booze! (I went in only twice; once to see what it was all about, and again during the Blizzard of '78 to get some needed food when all transit in the city was shut down and several feet of snow -- and neighborhood guns -- inhibited foot travel.) The area has much improved in the past three decades, but according to Google street view the liquor store is still there: <div style="text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj8hVLN1xPYNj6Jt7lCFLCqQ9tX7vWk4mSlLg-z7VuExANGbS1DUhqUIBr4mtJe388bRXneRyEQbAsNrXhJVKrwgJMp8JoBDBuDoT3XveF6u8j-6APhZYHLtWP5B-ue4Bzu8DQcuMEWHEGS/s1600-h/blanchards.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5383914675457072370" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj8hVLN1xPYNj6Jt7lCFLCqQ9tX7vWk4mSlLg-z7VuExANGbS1DUhqUIBr4mtJe388bRXneRyEQbAsNrXhJVKrwgJMp8JoBDBuDoT3XveF6u8j-6APhZYHLtWP5B-ue4Bzu8DQcuMEWHEGS/s320/blanchards.jpg" style="margin: 0px auto 10px; display: block; text-align: center; cursor: pointer; width: 320px; height: 186px;" /></a>In the 1970's "Liquor Land" was a large liquor store with a small grocery department named "Blanchard's." Click to enlarge. </div> Why does this odd store remind me of Wyeth, and more generally today's pharmaceutical industry? Because that industry has turned from what used to be a biomedical research & development industry with decent ethics and a small marketing arm, to large marketing industry with poor ethics and a small R&D arm. (Or, perhaps more accurately, a large marketing industry with poor ethics and a busywork section disguised to look like R&D. As a colleague noted in my post "Pfizer/Wyeth Merger And Sacrificing The Future: Laying Off Scientific Staff All Over The Place" <a href="http://hcrenewal.blogspot.com/2009/01/pfizerwyeth-merger-and-sacrificing.html">here</a>, a small fraction of prime scientist intellectual horsepower and time is actually spent on true R&D today, the rest wasted on feeding the bureaucratic corpulence that is the modern pharma research lab. He observed that "what we today call pharmaceutical R&D is in reality busywork disguised to look like R&D, in effect a well engineered, well managed, massively expensive failure.") Here is what led to my "pharmas have become large marketing firms with a small R&D effort" metaphor. It was a story in the local newspaper on ghostwriting. The glib quotes from Dr. Joseph Camardo, Wyeth's senior vice president of global medical affairs, on the practice of ghostwriting are simply stunning: <blockquote>Philadelphia Inquirer <a href="http://www.philly.com/philly/business/59905997.html" style="font-weight: bold;">Ghosts in the medical machine</a> Was drug research infected by ghostwriters? With Paxil suit in court, a Chadds Ford firm says it was ethical. <div class="article_timestamp"> Sun, Sep. 20, 2009 </div> By Miriam Hill Inquirer Staff Writer When GlaxoSmithKline P.L.C. marketers looked for doctors to promote the antidepressant Paxil, they called the project CASPPER. The name was more than just an offbeat tribute to the friendly cartoon ghost. It was a wink and a nod to "ghostwriting," a questionable practice in which scientists put their names on research written by someone else, usually a writer paid by a drugmaker. Ghostwriting critics say it disguises marketing material as scientific research. Charges of ghostwriting have been lobbed against many companies in recent years, including Glaxo, Wyeth, AstraZeneca P.L.C., and Merck & Co. Inc., often arising in lawsuits from consumers claiming a drug hurt them.... Documents released in connection with 8,000 lawsuits filed against Wyeth over Premarin and Prempro show that the company, which employs several thousand people in Collegeville, paid a medical-writing firm to produce articles from 1998 to 2005 that allegedly downplayed the risks of hormone treatment and emphasized benefits. In 2002, researchers stopped a landmark federal study after finding that menopausal women who took certain hormones had an increased risk of breast cancer, heart disease, and stroke. "Ghostwriting was used to sway physician opinions to favor hormone use as disease prevention long after that was a scientifically defensible position," Fugh-Berman [writer Adriane Fugh-Berman - ed.] said. Joseph Camardo, Wyeth's senior vice president of global medical affairs, called Fugh-Berman's view "baseless." Medical opinion evolves, he said, and the papers in question reflected scientific understanding then. He also said the authors alone controlled the content and writing of the papers, though some did have outside help paid for by Wyeth. "It's really being misrepresented as something we wrote and paid for that said what we thought it should say," Camardo said. "But the authors were not paid, and the authors had the final say." ... Studies on ghostwriting have suggested that anywhere from 8 percent to 75 percent of articles in medical journals may involve the practice.</blockquote> Aside from the point I raised in my post "Has Ghostwriting Infected The Experts With Tainted Knowledge, Creating Vectors for Further Spread and Mutation of the Scientific Knowledge Base?" <a href="http://hcrenewal.blogspot.com/2009/08/has-ghostwriting-infected-experts-with.html">here</a> regarding possible severe contamination of the literature and therefore of "expert knowledge" as it exists today, Camardo's response raises a cornucopia of questions. Regarding "Medical opinion evolves, he said, and the papers in question reflected scientific understanding then": <ul><li>Whose scientific opinion do they reflect, exactly? </li><li>Does Camardo believe these ghostwritten papers, usually written by party "A" but with authorship claimed by party "B" (usually prominent academic physicians often nurtured by the industry into the role of "key opinion leaders", KOL's) are objective?</li><li>Does Camardo actually believe most of the content comes from party "B" rather than party "A" in these papers? </li><li>Does Camardo understand that paying a MECC (Medical education & communications company) or other firm to write scientific papers puts the author(s) of those papers in a conflict of interest position relative to the paying sponsor, injurious to objectivity?</li><li>Is Camardo that naive to believe a paid writer would "diss" the holder of his or her paycheck?</li></ul>Regarding "the authors alone controlled the content and writing of the papers, though some did have outside help paid for by Wyeth": <ul><li>Which authors is he referring to? </li><li>The ghostwriters?</li><li>Wyeth scientists?</li><li>Academics claiming authorship? </li><li>Was the "outside help" from Wyeth "authors" to the ghosts, or from the ghosts to Wyeth "authors", or from Wyeth to the academics claiming authorship, or what? </li><li>Can Camardo produce statistics on what % of article content on ghostwritten articles Wyeth sponsored were written by the ghost vs. written by Wyeth scientists and/or the claimed academic author? If not, why not? And if not, why should any intelligent person not assume the papers are, say, 99% the product of the hired guns?</li></ul>Regarding "the authors were not paid, and the authors had the final say": <ul><li>Again, which author(s) is he referring to?</li><li>In terms of the ghosts, I assume they were not working for the MECC's for free.</li><li>In terms of the academics and KOL's claiming authorship, they (maybe!) were not paid in money, but instead in the valuable academic currency of a publication in a major biomedical journal. </li></ul>To claim the KOL's were "not paid" is disingenuous. In fact, I find his entire argument disingenuous, a play on words, PR "spin" completely callous to the needs for scientific objectivity, the advancement of science, and ultimately to patient's lives. This is marketing, with poor ethics, in the extreme. Being somewhat familiar with authorship issues as former Director of Published Scientific Information Resources and The Merck Index (of Chemicals, Drugs & Biologicals), 13th ed. at Merck Research Labs, I further pointed out in my post "Wyeth: Ghostwritten Papers Fake, But Accurate" <a href="http://hcrenewal.blogspot.com/2009/07/wyeth-ghostwritten-papers-fake-but.html">here</a>, that: <blockquote>... in addition to the violation of accepted practices of authorship, such as specified by <a href="http://www.docstoc.com/docs/922992/Guidelines-for-the-Conduct-of-Research-at-NIH">NIH</a> and the <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1416675">International Committee of Medical Journal Editors</a>, among others, such lucky authors [i.e., those who claim authorship of ghostwritten papers] get to "count" such papers in their academic portfolios, presumably also in violation of their own institutional policies and guidelines for fair attribution and intellectual honesty, e.g., <a href="http://www.hms.harvard.edu/fa/attribution.html">here</a> [Harvard - ed.] </blockquote> These industry practices and Camardo's position may be based on: <ul><li>Ignorance of accepted practices of authorship of the NIH, the International Committee of Medical Journal Editors, and most academic institutions, or perhaps: </li><li>Cavalier dismissal of these practices for pecuniary reasons. </li></ul> Is Camardo informed and upfront? Inept? Disingenuous and dishonest? That is up to the reader to decide. In my aforementioned post "<a href="http://hcrenewal.blogspot.com/2009/07/wyeth-ghostwritten-papers-fake-but.html">Wyeth: Fake but Accurate</a>" I'd also noted Wyeth attorney Stephen Urbanczyk acknowledging that the ghostwritten articles were part of a marketing effort. But he said that they were also "fair, balanced, and scientific." More spin. This raises the following observation. It is said that you can judge people by the company they keep. I also believe that: <blockquote style="font-weight: bold;">You can judge companies by the people they keep. </blockquote> This raises the following very serious questions: <ul><li>Is the presence of a senior vice president of global medical affairs and a lawyer with such views on ghostwriting representative of the senior executive leadership's views on dissemination of biomedical scientific information? </li><li>Is their presence reflective of the views of Wyeth's Board of Directors?</li></ul> If so, then the objectivity of any article about Wyeth drugs is called into question, and physicians and patients should utilize Wyeth drugs (and literature on them) with great caution. -- SS<div> </div><div>Addendum: this from the <a href="http://thestar.blogs.com/ethics/2009/09/wyeth-ghostwriting-documents-now-searchable.html">Medical Ethics blog</a>:</div><div><a href="http://www.nytimes.com/2009/08/05/health/research/05ghost.html?pagewanted=1&_r=1" style="text-decoration: none; color: rgb(51, 102, 153);"></a><blockquote><a href="http://www.nytimes.com/2009/08/05/health/research/05ghost.html?pagewanted=1&_r=1" style="text-decoration: none; color: rgb(51, 102, 153);">Recently released</a> court documents in a lawsuit against drug giant Wyeth, thanks to a court action by the New York Times and <a href="http://www.plosmedicine.org/home.action" style="text-decoration: none; color: rgb(0, 51, 102);">PLoS Medicine</a>, are now searchable at a University of California, San Francisco web site.The Wyeth documents are the latest made searchable at the <a href="http://dida.library.ucsf.edu/" style="text-decoration: none; color: rgb(51, 102, 153);">Drug Industry Document Archive</a>, or DIDA, which archives the documents from <a href="http://dida.library.ucsf.edu/documents.jsp" style="text-decoration: none; color: rgb(0, 51, 102);">several high-profile cases</a>.... The documents were first made available last month on the <a href="http://www.plosmedicine.org/static/ghostwriting.action" style="text-decoration: none; color: rgb(0, 51, 102);">PLoS web site</a>, but were not searchable and difficult to sort through. The DIDA site now make it possible to search for documents by name, type or content. </blockquote></div><div>Also see "<a href="http://thestar.blogs.com/ethics/2009/08/ghostwriting-why-they-do-it.html">Ghostwriting: Why they do it</a>" at that blog.</div><div> </div><div>-- SS</div>

Wyeth, Ghostwriting, Dr. Joseph Camardo and a Big Liquor Store With a Little Grocery Department

Ghostwriting is a topic covered extensively at Healthcare Renewal, including at my post " Wyeth: Ghostwritten Papers Fake, But Accurate...

Đọc thêm »

A mysterious series for H.G. Wells

You might have noticed an unexplained set of doodles on the Google homepage and a couple tweets from our official Twitter stream, <a href="http://twitter.com/google">@google</a>, over the last two weeks. On September 5th, we posted a doodle with the abduction of our second 'o' and a coded tweet from its alien captors: 1.12.12 25.15.21.18 15 1.18.5 2.5.12.15.14.7 20.15 21.19, which translates into "All your O are belong to us" (a nod to the Japanese video game, <a href="http://en.wikipedia.org/wiki/Zero_Wing">Zero Wing</a>). <a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjInnmNhYlSX93geyP9B0N07i7tGN01Ow0tLtSdr-mzNjrYuhAh7OtkIYCKrQ2Jv0Jp-aMeeI-3BeI-CllUG72D0LFgbZM0oq9xrz7qXwzxs46MziZBkJvSmkZ8zBTeM76z3e60xfj3Xy2r/s1600-h/go_gle_1.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5383766814533279858" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjInnmNhYlSX93geyP9B0N07i7tGN01Ow0tLtSdr-mzNjrYuhAh7OtkIYCKrQ2Jv0Jp-aMeeI-3BeI-CllUG72D0LFgbZM0oq9xrz7qXwzxs46MziZBkJvSmkZ8zBTeM76z3e60xfj3Xy2r/s400/go_gle_1.jpg" style="display:block; margin:0px auto 10px; text-align:center;cursor:pointer; cursor:hand;width: 400px; height: 144px;" /></a><div style="text-align: left;"> </div><div>We were delighted that people around the world played along with us and shared their <a href="http://news.google.com/news/more?pz=1&cf=all&ncl=dFakfc8c2RaGIzMGOqyHjkY0-FAjM">theories for why we would have posted this "unexplained phenomenon</a>." Ten days later, the UFO returned. This time, it was to leave its mysterious mark on the fields. <a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjMnSjINuF3Dp4KDxuuiiiUkdCWUTjV9Z4bXM-PtPV6fumO1Ou5NoHJyLOdDZOkJoa5ylWOmFtHNl2-fZmLFHmKeceIGAQfTMQjnWd2i50hgk-jksIIBJ-d2Rm_Fh8lY2b82uVPFRcmp82L/s1600-h/goog_e_2.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5383766823458096754" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjMnSjINuF3Dp4KDxuuiiiUkdCWUTjV9Z4bXM-PtPV6fumO1Ou5NoHJyLOdDZOkJoa5ylWOmFtHNl2-fZmLFHmKeceIGAQfTMQjnWd2i50hgk-jksIIBJ-d2Rm_Fh8lY2b82uVPFRcmp82L/s400/goog_e_2.jpg" style="display:block; margin:0px auto 10px; text-align:center;cursor:pointer; cursor:hand;width: 400px; height: 144px;" /></a> <div style="text-align: left;">While the link from the doodle to a search for "crop circles" didn't provide any more clues, we also tweeted the lat/long coordinates of <a href="http://maps.google.com/maps?f=q&source=s_q&hl=en&geocode=&q=horsell+common+england&sll=37.0625,-95.677068&sspn=38.365962,56.513672&ie=UTF8&ll=51.343481,-0.553436&spn=0.029595,0.055189&t=h&z=14&iwloc=A">Horsell Commons</a>, the location of the first alien landing in H.G. Wells 1898 classic, <a href="http://books.google.com/books?q=the+war+of+the+worlds&btnG=Search+Books">The War of the Worlds</a>. Some of you <a href="http://www.guardian.co.uk/books/2009/sep/15/google-crop-circle-hg-wells">figured out what we were doing</a>, but we weren't ready to reveal it all just yet. </div> Now, we're finally acknowledging the reason for the doodles with an official nod to Herbert George, who would be 143 years old today.  <a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjkpujaaVQWspdLcIyg1IizoDRmHIl7SLaA7l-T1HxWr53_idWEIC26x_Tx2yiUXikIBrPrteoPxPpBk6Ti7TfUujXq5GauHXMGy_lkoAQ2bm0IJrlzy_GP2lYHA8p5RyQMnNlkdHnY4bs_/s1600-h/hg_wells_birthday2009_part3_highres.jpg" onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5383767868197563858" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjkpujaaVQWspdLcIyg1IizoDRmHIl7SLaA7l-T1HxWr53_idWEIC26x_Tx2yiUXikIBrPrteoPxPpBk6Ti7TfUujXq5GauHXMGy_lkoAQ2bm0IJrlzy_GP2lYHA8p5RyQMnNlkdHnY4bs_/s400/hg_wells_birthday2009_part3_highres.jpg" style="display:block; margin:0px auto 10px; text-align:center;cursor:pointer; cursor:hand;width: 400px; height: 181px;" /></a> <div style="text-align: left;">Inspiration for innovation in technology and design can come from lots of places; we wanted to celebrate H.G. Wells as an author who encouraged fantastical thinking about what is possible, on this planet and beyond. And maybe have some fun while we were doing it. </div></div><div> The invasion of the logo by alien crafts and pods makes our series complete, but you'll have to read the book to find out how Wells' story really ends. Posted by Micheal Lopez, Web Design Lead</div>

A mysterious series for H.G. Wells

You might have noticed an unexplained set of doodles on the Google homepage and a couple tweets from our official Twitter stream, @google , ...

Đọc thêm »